Health & Biotech Success Stories
Graphene Transistors for High-Density Brain-Computer Interfaces
The GphT-BCI project, coordinated by INBRAIN Neuroelectronics & Institut Català de Nanociència i Nanotecnologia (ICN2), will pave the way for the clinical translation of brain-mapping neural interfaces based on graphene-transistor arrays for brain-computer interfaces.
INBRAIN harnesses the extraordinary material properties of Graphene, the world’s thinnest material, to build safe, noninvasive and highly efficient neural solutions.
Automated biomedical image analysis for diagnosis and drug discovery
Ariadne developed deep-learning tailored image analysis solutions for screening assays.
Applications from automated neuron tracing, cell image & organelle segmentation, and electron microscopy image analysis.
Sustainable agriculture through carbon capture
Deep Branch is creating proprietary CO2-to-protein processes directly utilising clean CO2 and hydrogen to generate single-cell protein for animal nutrition.
Their technology enables businesses to lower their carbon footprint without impacting their operational costs.
A regenerative gene repair platform to restore muscle function in muscular dystrophy patients
MyoPax’s platform introduces a new class of regenerative therapies that repair genetic mutations ex vivo and rebuild healthy muscle with engineered human muscle stem cells.
Their curative approach combines CRISPR-based gene editing with patented stem cell manufacturing.
Plasma-based technology for sustainable plastic packaging
IonKraft develops a proprietary coating system to apply high-performing coatings that meet industry needs, while also making them from sustainable barrier plastic.
Their coating technology makes plastic barriers lighter, fully recyclable and reusable, and enables the use of recyclate.
Versatile, Personalised, Antimicrobial and Anti-Inflammatory Coatings for Medical Devices
SPARTHA Medical developed multifunctional coatings specially formulated to prevent infection and bacterial resistance.
They demonstrated the efficacy of their solution against a wide range of bacteria (Gram+ and Gram-) and methicillin-resistant Staphylococcus aureus (MRSA).
Robotics tools for Surgery & Orthopaedics 4.0
Ganymed creates robotics tools for surgical suites that are lightweight and powered by dedicated software solutions for increased efficiency and safety.
Their surgery tools improve both patient outcomes and surgeon experience.
Harnessing biotechnology & machine learning to create bio-based materials and ingredients
Bioweg produces bio-based, sustainable, and green ingredients that can replace microplastic additives in cosmetics.
Their platform enables the development of fermented bio-based ingredients for the food industry to replace highly-processed irritant additives.
Genomics-informed drug discovery for precision oncology
Epigene Labs focuses on discovering cancer treatments by leveraging advanced AI and genomic data in designing tailored therapeutic approaches.
Their platform enables both brand-new drug discovery & drug repurposing for the largest patient benefit.
Miniaturised respiratory assist to treat acute lung failure patients using a breakthrough hyperbaric technology
HBOX Therapies developed Miniaturised Respiratory Assist, an innovative hyperoxygenation therapy that combines unrivalled blood oxygenation and CO2 removal to treat acute lung failure patients.
Miniaturised Respiratory Assist therapy has outstanding cost-effectiveness and improved patient outcomes by avoiding or limiting the need for invasive mechanical ventilation and further respiratory deterioration in these patients.
AI-powered remote monitoring and predictive care to reduce heart failure hospitalisations and improve patient outcomes
Implicity is enhancing its remote monitoring platform with an advanced AI module that predicts heart failure events using data from cardiac implantable electronic devices.
Their technology enables early detection with streamlined alert management and care coordination, enabling a shift in chronic heart failure care and reducing the hospitalisation burden.
Minimally invasive graphene-based implant for treating brain disorders
The MINIGRAPH project aims to develop and validate innovative brain implants with closed-loop neuromodulation capabilities controlled by implanted electronics units and miniature arrays of graphene microelectrodes.
The project will introduce a minimally invasive, high-precision implantation procedure using a single small skull incision.
Developing drugs for undruggable conditions
ProSion created a drug discovery platform building new drugs from molecules.
Their technology uses LEGO-like chemical building blocks to develop new and effective drugs for hard-to-treat diseases–such as aggressive cancer forms.
Effective and affordable treatment for heart failure
Adjudicator delivers reBEAT, a revolutionary technology to mechanically support both sides of the heart, which does not directly contact blood and can be easily implanted.
Their system offers high cost-effectiveness at <50% of the cost of heart transplantations and ventricular assist devices, which are the gold standard treatment today.
Minimally invasive treatment for Aunerysms
Endoron Medical is redefining aneurysm treatment with Aortoseal, a fixation and sealing implant which requires only minimally invasive surgery.
Their technology can deliver stability repair compared with open sutured repair while avoiding such procedures for quicker recovery times. which combines.
Novel class of therapeutics for PTSD treatment and other neurodegenerative disorders
ReST Therapeutics developed breakthrough therapies to treat complex central nervous system disorders, in particular, Post-Traumatic Stress Disorder under its various forms, followed by Alzheimer's Disease.
Their lead candidate - FENM, is a novel and proprietary chemical entity that facilitates stress release and neuroprotection without triggering adverse side effects of current NMDA-targeting drugs.
Targeted therapies that break through the protective barriers of solid tumours
Apmonia Therapeutics’ platform uses advanced molecular simulations to design small peptides that disrupt tumour-promoting interactions, enhancing the effectiveness of existing immunotherapies.
Their lead candidate, TAX2, has demonstrated significant tumour suppression and improved immunotherapy outcomes in multiple preclinical models.
Introducing a novel 3D image-based sequencing platform designed to lower the cost and increase the speed of genome analysis
Single Technologies’ system replaces conventional flat flow-cell sequencing with a cylindrical hydrogel matrix, enabling high-throughput sequencing in 3D using fast, parallel confocal imaging.
Their approach not only reduces sequencing costs to under €10 per genome but also opens up new possibilities in genomics and diagnostics.
Leader of electrotherapeutic solutions for bone and tissue regeneration
Intelligent Implants creates data-enabled and minimally-invasive medical implants for active monitoring and therapy.
Their medical devices enable the tailoring of treatments to patient needs and facilitate decision-making for healthcare professionals.
A smart way of diagnosing and treating sleep apnea
Sunrise developed We have a 3-gram sensor to diagnose sleep with a gold standard quality offering a new way to measure brain commands at night, with unprecedented clinical results.
Their platform can positively impact the lives of more than 1 billion people.
Harnessing the power of AI for cardiovascular drug discovery
Genome Biologics Integrates AI-driven target and drug identification with preclinical testing enabling faster drug discovery informed by data.
They focus on developing new cardioprotectives that can protect the hearts of cancer patients treated with chemo.
Enabling affordable and sustainable cultivated meat with a first-in-class growth medium
Multus Biotechnology devised Proliferum M, a complete all-in-one growth medium solution where growth factors are not only produced sustainably but also engineered for maximal stability and growth stimulation efficacy.
Their technology is based on proprietary machine learning and an ultra-scalable yeast production system that abates production costs by 85 times.
Antibiotics sensitivity testing
The BE FAST project, coordinated by SoundCell, will aim to develop high-volume manufacturing technology for Rapid Antibiotic Susceptibility Testing based on detecting microorganisms' vibration on ultrathin micron-sized graphene drums.
SoundCell system enables doctors to identify and administer the right type of antibiotics based on infection type.
Real-time monitoring and risk assessment for air contamination control
Plair created specialised solutions for detection and early warning of changes in air quality for sterile manufacturing and research
Their technology has a wide range of applications from detection of bioaerosols and allergens, to microbial detection with the benefit of autonomous measurements for increased accuracy and reliability.
Absorbable, hemocompatible stents with stealth coating for safer pediatric and adult cardiovascular interventions
The StealthStent project, coordinated by Biomodics with the participation of GrownValve, is pioneering the first stent specifically designed for children with congenital heart disease.
Their stent combines a bioresorbable backbone that dissolves in six months, allowing natural vessel growth, with a novel zwitterionic polymer-based stealth coating that prevents foreign body reactions. Their device is expected to reduce severe complications, migration, and breakage risks, ultimately reducing the burden on young patients.
Emotion recognition for applications in psychiatric treatment
Cephalgo developed the first accurate, remote & continuous emotion tracker to monitor treatment effectiveness and predict the best course of treatment for a given patient profile.
Their technology combines electroencephalography & an AI-driven emotion recognition algorithm. It can detect emotions with 88% accuracy & predict the best treatment to reduce the trial-and-error approach currently employed in psychiatry.
A painless, non-invasive DNA methylation test that detects melanoma in early stages
Mitra Bio’s technology combines a gentle skin tape-strip sampling method with a proprietary DNA methylation panel to identify melanoma with over 95% specificity and sensitivity.
Their innovation enables early and accurate melanoma detection at the GP clinic or even at home, reducing reliance on invasive biopsies.
Integrated photonic sensing for affordable bioprocess monitoring for pharma and chemistry industries
InSpek is advancing biomanufacturing with a compact multi-sensor-on-a-chip platform based on waveguide-enhanced Raman spectroscopy and photonic integrated circuits.
Their technology combines key bioprocessing sensors, including Raman, temperature, pH, and dissolved oxygen, into a single, non-invasive device. It enables faster, more accurate, and cost-effective monitoring in biomanufacturing.
De-risking the drug discovery process
Vitala brings together multiple new patented technologies to develop an efficient and ethical efficacy-of-treatment analysis system that will revolutionise drug discovery and personalised medicine.
Through Hyperpolarized-Magnetic Resonance Spectroscopic Imaging, organ-on-a-chip technology, and advanced data analytics, Vitala can deliver deep insights into metabolic kinetics at the cellular and tissue level, in real-time and with micromolar sensitivity.
Advancing brain disease diagnostics with self-propelled microrobot for 3D brain biopsies
Robeauté is redefining neurosurgery with an active microrobot capable of navigating complex brain structures and performing targeted biopsies.
Their robots enable minimally invasive access to previously unreachable tumour sites, supporting safer, more accurate diagnostics and paving the way for personalised treatment for brain diseases.
Environment-friendly mosquito control with pheromones
Molecular Attraction pioneers in mosquito-specific phagostimulants and pheromones.
Their solution enables the control of mosquito behaviour using minute quantities of highly effective, affordable and perfectly green semiochemicals.
Disrupting the Migraine continuum of care for resource-constrained settings
The TARA project will disrupt the continuum of care and referral pathway by creating a more effective non-surgical solution that reduces cost and risk and, therefore, increases accessibility to more physicians and patients.
The consortium will develop a novel platform for treating chronic migraine that will be particularly applicable to resource-restricted environments and targeting underserved patients.
Next-generation wound care
Piomic Medical developed a medical device to treat hard-to-heal and chronic wounds.
Their portable, hand-held device combines optical and magnetic stimulation that promotes faster wound healing.
Leading supplier of dynamic analysis instruments for cell biology research and diagnostics
Lumics unlocks possibilities for the measurement of biological forces and interactions to enable a better understanding of disease state.
Ideally suited for immunotherapy research, such as novel therapies using CAR T, TCR T, cell engagers, and CAR-NK / NK cells.
Advanced point-of-care ultrasound technology for real-time stroke diagnosis and brain care
Resolve Stroke is developing SYLVER, a cutting-edge ultrasound system that brings fast, high-precision imaging directly to the patient’s bedside.
SYLVER uses software-based technology to harness 100% raw ultrasound data, enabling advanced 3D imaging and deeper diagnostic insights, offering CT-equivalent stroke diagnostics using portable ultrasound.
A game-changing bioreactor for sustainable production of active pharmaceutical ingredients
Alkion develops a biorefinery to produce top quality active pharmaceutical ingredients and extracts in plants in a sustainable and cost-effective way.
Their core technology combines a disruptive patented automated bioreactor-AlkaBurst2.0 with unique know-how on gene expression methods, culture media and extraction.
Innovative heart failure management with AI-driven voice monitoring for early detection and intervention
Noah Labs is developing a smart medical device that uses AI to analyse a patient’s voice and detect early signs of heart failure, up to 3 weeks before symptoms worsen.
By giving doctors and patients more time to act, their technology can reduce hospital visits, lower mortality, and cut healthcare costs by over 30%.
An advanced surgical system that transforms laparoscopic procedures with in-body instrument switching
Even simple keyhole surgeries require 20 to 50 tool changes. Symphera’s technology replaces time-consuming manual tool exchanges with an automated mechanism that switches between up to eight instruments inside the body.
Their system enables shortening surgery times by up to 30 minutes and improving precision and outcomes, setting a new standard for efficiency and safety in minimally invasive surgery.
An active immunotherapy for the treatment of osteoarthritis
Peptinov developed an active immunotherapy that can halt inflammation-driven destruction of the cartilage in the joints in osteoarthritis.
Their vaccine-like approach stimulates the patient’s own immune system to produce antibodies against the excess production of inflammatory proteins.
Analytical platform tailored for cell & gene therapy manufacturing
The PAT4CTG project aims to enable in-line continuous monitoring of key cell culture parameters during therapy manufacturing.
The consortium will develops a self-contained instrument that connects miniaturized biosensor technologies to a novel bioreactor to allow automation of the entire cell therapy manufacturing process in a closed system.
Graphene-based neural interfaces for the treatment of neurological diseases
INBRAIN Neuroelectronics develops a complete platform of intelligent neuroelectronic interface systems powered by Graphene dots.
Their graphene-based neural implants will have the capability of reading single neural cells, detecting therapy-specific biomarkers and triggering adaptive responses for increased outcomes in personalised neurological therapies.
A decision-making support platform for surgical suites and clinicians
Avatar Medical delivers 3D imaging solutions for surgical suites–it is the first photorealistic, machine learning-enabled data & image visualisation platform–supporting decision-making for clinical applications.
Their imaging system will assist surgeons in planning and implementing specific procedures.
Optimising and predicting antidepressant efficacy using multi-omics analysis and AI-predictive tool
The OPADE project will identify critical biomarkers that support the decision-making process of healthcare providers by focusing on the microbiota–brain axis, which plays a central role in mental health and major depressive disorders.
By studying genetics, epigenetics, microbiomes and inflammatory networks to establish patient profiles, the project will predict and optimise antidepressant efficacy.
Bionic bioreactor tailored for sensitive stem and immune cells production for cell therapy applications
BioThrust’s ConfyCell recreates a natural, low-stress environment for stem and immune cells, enabling industrial-scale cultivation with higher yields and scalability.
Their bioreactor will help tackle a key bottleneck for cell therapies by replacing outdated bioreactor systems with a scalable, cell-friendly solution.
Delivering faster and more precise microbiome profiles
Perseus Biomics creates tools for precise and resource-efficient microbiome analysis for researchers and clinicians.
Their technology empowers microbiome research, therapeutics, and personalised medicine.
Improving neurosurgical outcomes with the first-ever 3-in-1 sutureless patch for dual repair
Nurami’s ArtiFix is a bio-absorbable, biocompatible patch that seals and heals the dura while preventing cerebrospinal fluid leaks.
Their patch forms an adhesive layer that enables sutureless fixation and watertight sealing, while promoting healing.
Medical robotics for early mobilisation for critical care patients
Reactive Robotics developed AI-driven robotic assistance system for the early mobilisation of ICU patients.
Their robotic system guarantees early mobilisation is delivered safely to all ICU patients, accelerating recovery by 20%, reducing treatment costs, increasing ICU capacity by 27%, and improving patient outcomes.
Delivering new treatments for neurodegenerative diseases
BrainEver creates a groundbreaking platform to treat neurodegenerative diseases based on a family of transcription factors called Homeoproteins, which are proteins that regulate age-dependent mechanisms related to neurodegeneration.
Pre-clinical results suggest that homeoproteins-based therapy can help increase neuronal survival and function, halting disease progression.
Scalable AI-powered radiology to accelerate precision medicine and clinical trials
Raidium is developing the first interactive, multimodal foundation model for radiology, enabling radiologists and clinicians to generate scalable biomarkers without data pre-processing.
Their human-centric platform reduces radiologist workload, speeds up clinical trials, and supports the shift toward personalised medicine.
Accelerating drug discovery with a closed-loop platform combining generative AI and robotics
Iktos is integrating AI-driven molecular design with automated synthesis and testing to significantly shorten drug discovery timelines and reduce failure rates.
Their platform enables the in silico generation of novel drug candidates, rapid planning of synthesis routes, and real-time data feedback. Taken together, this will allow shortening of the discovery pipeline from 5 years to just 2.
A breakthrough technology for the early diagnosis of osteoporosis and other bone-related diseases
Porous develops a solution to replace current imprecise diagnostic methods for osteoporosis.
Their technology is based on quantitative ultrasound combined with patented intelligent algorithms that can measure the cortical bone quality down to the microscopic pore level–enabling precise diagnosis and early treatment.
Gene writing platform unlocking the full potential of genetic therapies with unmatched precision, efficiency, and safety
Integra Therapeutics is advancing gene therapy with technology combining RNA-guided nucleases and programmable transposases to insert large DNA fragments safely and accurately.
Their technology was validated in both ex vivo and in vivo models, paving the way to treat previously untreatable genetic and neoplastic diseases, expanding the reach of precision medicine and transforming patient care.
A fully synthetic blood substitute that unlocks warm perfusion for organ preservation, tripling viability and expanding the donor-organ pool
Vivalyx is introducing a synthetic perfusion solution that enables scalable, blood-free organ preservation at body temperature, outperforming blood by 3x in maintaining organ function and viability.
Their technology has the potential to expand the pool of transplantable organs by enabling the resuscitation of marginal organs and providing real-time viability assessment.
Implantable neuromodulation technology for stroke rehabilitation
CorTec aims to provide a novel implantable device for stroke rehabilitation.
Their device can provide recording capabilities & closed-loop therapy, expand therapeutic options, and provide insights into future therapy development.
Deep-learning-guided detection and diagnostic of prenatal medicine
Sonio created an AI one-stop modular software platform to guide OBGYNS & sonographers during fetal ultrasound.
The core of the technology is the Clinical Brain platform with a unique mix between fetal medicine & AI that can detect 1.6k anomalies & 450 syndromes–helping to revolutionise prenatal medicine.
Next-generation laboratory tools for rapid, scalable testing
Nagi Bioscience created organ-on-chip technology that allows scalable, customisable assays for ethical in vivo testing.
Their “Organism-on-Chip” technology can boost innovation and efficiency in the pharmaceutical, cosmetic, and chemical industries.
The future of heart failure management with real-time, multiplex biomarker detection
Omini Labs’ handheld point-of-care device simultaneously measures four key biomarkers from a single drop of blood.
Their technology matches gold-standard benchmarks, ensuring continuum care after hospital discharge, reducing re-hospitalisation and mortality rates by at least 30%.
Developing next-generation therapies for cancer and infectious diseases
TC Biopharm bio-engineered a solution that enables off-the-shelf immunotherapy by using donor T-cell.
Their approach enables therapy that is easy to use, widens patient access, improves the quality of life, and costs less than on-the-market alternatives.
Vaginal Microbiome Screening service to provide diagnosis, disease risk evaluation, and aftercare
Daye is set to revolutionise women's healthcare by providing a home-based gynaecological test kit for testing for STIs, infections and HPV.
Their patent-protected technology enables DNA extraction to test 16 different biomarkers simultaneously to offer comprehensive aftercare, including treatment planning & doctor consultations.
AI-enabled Intelligent lab on fibre for identification and quantification of disease biomarkers
iLoF is pioneering an AI-based platform to accelerate the future of personalised drug discovery & development.
Their technology uses advanced AI & photonics to detect label-free nanosized biomarkers in biological liquid samples, to generate specific patient or disease signatures for drug discovery purposes.
Creating antimicrobials for future pandemics
Omnix Medical is developing an arsenal of novel antibiotic agents for the treatment of infections involving drug-resistant bacteria.
Their drug discovery pipeline is based on natural antimicrobial peptides, genetically engineered to be compatible with therapeutic use.
Life-saving heart valve solutions for the future of medicine
Grown Valve fulfils an unmet clinical need for a safe prosthetic valve that can help 400,000 patients globally.
Their solution eliminates the need for repeated heart valve replacement surgery and lifelong medication.
A combination treatment effective against all critical multidrug-resistant pathogens
Antabio develops a combination of existing antibiotics and their proprietary, best-in-class serine-β-lactamase inhibitor, which makes pathogens susceptible to antimicrobials, intended for the treatment of hospital-acquired infections caused by drug-resistant pathogens.
Their treatment has been pre-clinically proven to be efficacious against Gram-negative antimicrobial-resistant bacteria.
First-in-class technology for microbiome engineering
Eligo Bioscience technology enables the delivery and expression of therapeutic DNA that allows modulation of the microbiome’s composition and function to address the human disease with unprecedented precision.
Their patent-protected tech can change the way many diseases are treated.
Medical device for heart failure treatment
Restore Medical engineered ContraBand, an implantable device aiming to restore heart function in patients suffering from left ventricle failure.
ContraBand’s benefits include a built-in fail-safe for full reversibility of functionality, tremendous ease of use due to its proprietary stеnt-within-a-stеnt design and transcatheter delivery system, and full clinical flexibility to be compatible with pharmacotherapies and other medical devices.
